Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799918 | 1.00 | KMT2A (0.45) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL30701645 | 0.92 | MAPT (0.39) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL30701702 | 0.92 | ALOX5 (0.41) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL24682183 | 0.92 | MAPT (0.39) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL24682166 | 0.92 | ALOX5 (0.41) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL24683203 | 0.90 | HSP90AA1 (0.39) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL29799821 | 0.90 | HSP90AA1 (0.39) | KMT2ARAB9ANPC1MAPTLMNA | |
| SCHEMBL24682198 | 0.90 | TSPO (0.40) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29800055 | 0.90 | TSPO (0.40) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24683856 | 0.88 | ALOX5 (0.43) | KMT2AMAPTLMNAALOX12SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |