SCHEMBL24682245

SCHEMBL24682245

O=C1C(c2ccccc2)C(=O)N(CCO)C(=S)N1CCO

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 4/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 2/20 0.39
SLC18A3 Q16572 1/20 0.39
MAPK1 P28482 2/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
HTR2B P41595 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
HEXA P06865 1/20 0.36
HEXB P07686 1/20 0.36
HPGD P15428 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24682250 0.84 APEX1 (0.45) MAPTALDH1A1LMNAKDM4EMAPK1
SCHEMBL9357957 0.78 LMNA (0.40) MAPTALDH1A1LMNATSHRKDM4E
SCHEMBL24682251 0.78 EP300 (0.55) MAPTALDH1A1TSHRKDM4ECYP1A2
SCHEMBL6294237 0.73 KMT2A (0.46) MAPTALDH1A1LMNATSHRKDM4E
SCHEMBL11631635 0.72 CA12 (0.53) MAPTALDH1A1LMNAKDM4EMAPK1
SCHEMBL24682244 0.71 ALDH1A1 (0.32) MAPTALDH1A1LMNATSHRKDM4E
SCHEMBL377908 0.70 LMNA (0.66) MAPTALDH1A1LMNATSHRKDM4E
SCHEMBL15131561 0.67 ELANE (0.64) MAPTALDH1A1LMNATSHRKDM4E
SCHEMBL24682780 0.67 MEN1 (0.31) MAPTALDH1A1HPGDMEN1KMT2A
SCHEMBL15978121 0.66 LMNA (0.40) MAPTALDH1A1LMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11435667-B2 Polymer for organic bottom anti-reflective coating and bottom anti-reflective coatings comprising the same SK INNOVATION CO., LTD. (KR) 2022-09-06 US disclosed