Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799927 | 1.00 | LMNA (0.38) | LMNASMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL24683855 | 0.91 | HSP90AA1 (0.37) | LMNASMN1; SMN2MAPTTDP1HSP90AA1 | |
| SCHEMBL30664726 | 0.91 | HSP90AA1 (0.37) | LMNASMN1; SMN2MAPTTDP1HSP90AA1 | |
| SCHEMBL30701705 | 0.91 | MCL1 (0.39) | KMT2ARAB9AMEN1NPC1MCL1 | |
| SCHEMBL24683876 | 0.91 | MCL1 (0.39) | KMT2ARAB9AMEN1NPC1MCL1 | |
| SCHEMBL24683856 | 0.90 | ALOX5 (0.43) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL30701677 | 0.90 | ALOX5 (0.43) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL24683191 | 0.90 | HSP90AA1 (0.38) | LMNASMN1; SMN2KDM4ETDP1HSP90AA1 | |
| SCHEMBL30664665 | 0.90 | HSP90AA1 (0.38) | LMNASMN1; SMN2KDM4ETDP1HSP90AA1 | |
| SCHEMBL24683217 | 0.89 | MAPK8 (0.38) | MAPTKDM4EHPGDHSP90AA1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |