Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701686 | 1.00 | MEN1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL5165684 | 0.83 | MAPT (0.67) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL24683238 | 0.79 | MAPT (0.57) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5462763 | 0.79 | KMT2A (0.55) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL24683234 | 0.76 | KDM4E (0.59) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL30701675 | 0.76 | KDM4E (0.59) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31459976 | 0.76 | MAPT (0.75) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL31459864 | 0.76 | KMT2A (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL15172955 | 0.76 | KMT2A (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL2921771 | 0.75 | MAPT (1.00) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |