Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683234 | 1.00 | KDM4E (0.59) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL24683229 | 0.82 | MAPT (0.56) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24683228 | 0.76 | MEN1 (0.61) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL30701686 | 0.76 | MEN1 (0.61) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL4298608 | 0.74 | KDM4E (1.00) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL5165684 | 0.74 | MAPT (0.67) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL24683235 | 0.72 | ALDH1A1 (0.47) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL30701665 | 0.72 | ALDH1A1 (0.47) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL15172955 | 0.72 | KMT2A (1.00) | KDM4ECYP1A2CYP3A4CYP2C9MAPT | |
| SCHEMBL31459864 | 0.72 | KMT2A (1.00) | KDM4ECYP1A2CYP3A4CYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |