Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683887 | 0.88 | CA12 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30701701 | 0.88 | CA12 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24683863 | 0.77 | HSP90AA1 (0.43) | DYRK1AMEN1KMT2ALMNAMAPT | |
| SCHEMBL24683203 | 0.76 | HSP90AA1 (0.39) | DYRK1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL29799821 | 0.76 | HSP90AA1 (0.39) | DYRK1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL29800055 | 0.75 | TSPO (0.40) | DYRK1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL24682198 | 0.75 | TSPO (0.40) | DYRK1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL29799918 | 0.75 | KMT2A (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24683204 | 0.75 | KMT2A (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24683802 | 0.74 | NR1H4 (0.36) | DYRK1ANPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |