Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272205 | 0.89 | KDM1A (0.56) | KDM1AMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL9058890 | 0.80 | MEN1 (0.44) | KDM1AMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL10792326 | 0.79 | HDAC9 (0.41) | KDM1AMAOBKMT2APIN1 | |
| SCHEMBL6881229 | 0.78 | KDM1A (0.43) | KDM1AMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL7743674 | 0.78 | KDM1A (0.41) | KDM1AMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL3423844 | 0.77 | KDM1A (0.42) | KDM1AMAOBMEN1KMT2ATSHR | |
| SCHEMBL15547835 | 0.76 | KDM1A (0.44) | KDM1AMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL5674631 | 0.75 | HDAC9 (0.44) | KDM1AMAOBTSHRTDP1 | |
| SCHEMBL29527149 | 0.75 | KDM1A (0.41) | KDM1AMAOBMEN1KMT2ASIGMAR1 | |
| SCHEMBL12390025 | 0.74 | MEN1 (0.49) | KDM1AMAOBMEN1KMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4782252-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| EP-0738149-A4 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 1999-10-27 | — | — | EP | claimed |
| EP-0738149-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | claimed |
| CN-103923021-B | It is suitable for the heteroaryl compound of E1 activating enzyme inhibitors | 米伦纽姆医药公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-106008512-A | INHIBITORS OF E1 ACTIVATING ENZYMES | 千禧药品公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-101384591-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |