Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468439 | 0.78 | KDM1A (0.46) | KDM1AMAOBTSHRTDP1MEN1 | |
| SCHEMBL6881229 | 0.75 | KDM1A (0.43) | KDM1AMAOBTSHRTDP1MEN1 | |
| SCHEMBL9058890 | 0.73 | MEN1 (0.44) | KDM1AMAOBTSHRMEN1KMT2A | |
| SCHEMBL3423844 | 0.73 | KDM1A (0.42) | KDM1AMAOBTSHRTDP1MEN1 | |
| SCHEMBL5674631 | 0.72 | HDAC9 (0.44) | KDM1AMAOBTSHRTDP1HDAC9 | |
| SCHEMBL10792326 | 0.72 | HDAC9 (0.41) | KDM1AMAOBKMT2AHDAC9 | |
| Potassium Ion SCHEMBL5368119 | 0.70 | HDAC9 (0.39) | KDM1AMAOBTSHRTDP1HDAC9 | |
| SCHEMBL21788669 | 0.70 | KDM1A (0.36) | KDM1AMAOBTSHRTDP1MEN1 | |
| SCHEMBL1051970 | 0.69 | MAOB (0.39) | KDM1AMAOBTSHRTDP1MEN1 | |
| SCHEMBL29527149 | 0.69 | KDM1A (0.41) | KDM1AMAOBTSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476404-B | Transdermal composition comprising active agent layer and activating agent conversion coating | 帝国制药美国公司 | 2017-09-29 | — | — | CN | claimed |
| CN-108186611-A | Iodopropynylbutylcarbamate indane transdermal composition | 帝国制药美国公司 | 2018-06-22 | — | — | CN | disclosed |
| EP-0858328-A4 | STABLE COMPOSITIONS CONTAINING N-PROPARGYL-1-AMINOINDAN | TEVA PHARMA (IL) | 2001-07-11 | — | — | EP | disclosed |
| EP-0858328-A2 | STABLE COMPOSITIONS CONTAINING N-PROPARGYL-1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997012583-A2 | STABLE COMPOSITIONS CONTAINING N-PROPARGYL-1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1997-04-10 | — | — | WO | disclosed |