Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.46 |
| ▸ | DRD3 | P35462 | 12/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799620 | 0.78 | DRD2 (0.44) | DRD2DRD3OPRM1OPRK1DRD4 | |
| SCHEMBL24684779 | 0.78 | DRD2 (0.44) | DRD2DRD3OPRM1OPRK1DRD4 | |
| SCHEMBL246696 | 0.77 | DRD2 (0.56) | DRD2DRD3HTR2A | |
| SCHEMBL30002394 | 0.77 | HPGD (0.37) | DRD2 | |
| SCHEMBL253634 | 0.75 | MEN1 (0.55) | DRD2DRD3HTR2A | |
| SCHEMBL28600264 | 0.70 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL24719091 | 0.70 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL29799403 | 0.70 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL14852499 | 0.70 | MEN1 (0.56) | — | |
| SCHEMBL30208139 | 0.70 | MEN1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187206-A1 | DUAL-TARGET MU OPIOID AND DOPAMINE D3 RECEPTORS LIGANDS; PREPARATION AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-09-09 | — | — | WO | disclosed |