Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993273 | 0.92 | SMN1; SMN2 (0.47) | HPGDUSP2SMN1; SMN2CTSKKDM1A | |
| SCHEMBL28858721 | 0.82 | GRM5 (0.34) | HPGDUSP2SMN1; SMN2CTSKKDM1A | |
| SCHEMBL31715308 | 0.82 | USP2 (0.39) | HPGDUSP2SMN1; SMN2CTSKKDM1A | |
| SCHEMBL31322461 | 0.82 | CTSK (0.40) | HPGDUSP2SMN1; SMN2CTSKKDM1A | |
| SCHEMBL31357623 | 0.81 | HDAC1 (0.36) | HPGDUSP2SMN1; SMN2CTSKHDAC1 | |
| Formic Acid SCHEMBL29026228 | 0.80 | HPGD (0.34) | HPGDUSP2SMN1; SMN2CTSKKDM1A | |
| SCHEMBL31357715 | 0.77 | ADORA1 (0.36) | HPGDUSP2SMN1; SMN2CTSKHDAC1 | |
| SCHEMBL12350366 | 0.77 | CTSK (0.38) | HPGDUSP2SMN1; SMN2CTSKKDM1A | |
| SCHEMBL42476 | 0.77 | SMN1; SMN2 (0.48) | HPGDUSP2SMN1; SMN2CTSKHDAC1 | |
| SCHEMBL24684838 | 0.77 | DRD2 (0.46) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536661-A | Resolution of optically active diazaspiro [4.5] decane derivatives | 奥塔万特科学股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110177790-B | Resolution of optically active diazaspiro [4.5] decane derivatives | 奥塔万特科学股份有限公司 | 2022-10-14 | — | — | CN | disclosed |