Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975380 | 0.92 | MCHR1 (0.43) | P2RX7HTR2CMCHR1SCN2ASCN10A | |
| SCHEMBL24685249 | 0.92 | P2RX7 (0.41) | P2RX7TRPV1HIF1AHTR2CMCHR1 | |
| SCHEMBL24685259 | 0.88 | P2RX7 (0.42) | P2RX7TRPV1HTR2CMCHR1ROCK2 | |
| SCHEMBL24975525 | 0.88 | SCN2A (0.49) | P2RX7HTR2CMCHR1SCN2ASCN10A | |
| SCHEMBL24684942 | 0.88 | P2RX7 (0.44) | P2RX7TRPV1HIF1AHTR2CMCHR1 | |
| SCHEMBL24685226 | 0.87 | EIF4E (0.47) | P2RX7 | |
| SCHEMBL30057801 | 0.87 | EIF4E (0.47) | P2RX7 | |
| SCHEMBL24976316 | 0.86 | SCN2A (0.41) | P2RX7HTR2CMCHR1SCN2ASCN10A | |
| SCHEMBL24975303 | 0.86 | SCN2A (0.41) | P2RX7HTR2CMCHR1SCN2ASCN10A | |
| SCHEMBL24976322 | 0.84 | MCHR1 (0.44) | HTR2CMCHR1SCN2ASCN10AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022241257-A1 | NAMPT INHBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2022-11-17 | — | — | WO | disclosed |