Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 6/20 | 0.44 |
| ▸ | PTAFR | P25105 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057801 | 1.00 | EIF4E (0.47) | EIF4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29801044 | 0.92 | EIF4E (0.45) | EIF4ENPC1SMN1; SMN2GAANAMPT | |
| SCHEMBL24975327 | 0.92 | EIF4E (0.45) | EIF4ENPC1SMN1; SMN2GAANAMPT | |
| SCHEMBL24685258 | 0.87 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL24685016 | 0.87 | EIF4E (0.46) | EIF4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL24684923 | 0.86 | NAMPT (0.43) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24685246 | 0.85 | EPHX2 (0.39) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL24976704 | 0.85 | NPC1 (0.46) | NPC1RAB9AGAANAMPT | |
| SCHEMBL24684940 | 0.85 | HPGDS (0.54) | EIF4E | |
| SCHEMBL24975189 | 0.85 | LMNA (0.45) | NPC1RAB9AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022241257-A1 | NAMPT INHBITORS AND USES THEREOF | REMEDY PLAN, INC. (US) | 2022-11-17 | — | — | WO | disclosed |