Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24775494 | 0.87 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4964505 | 0.79 | CFB (0.46) | RIPK1 | |
| SCHEMBL23032154 | 0.79 | PRKCZ (0.40) | PRKCZ | |
| SCHEMBL23032156 | 0.79 | PRKCZ (0.40) | PRKCZ | |
| SCHEMBL17358798 | 0.77 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL17358800 | 0.77 | RIPK1 (0.61) | RIPK1 | |
| SCHEMBL24775482 | 0.77 | RIPK1 (0.44) | RIPK1 | |
| SCHEMBL24774484 | 0.76 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29087360 | 0.75 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3RIPK1 | |
| SCHEMBL29995030 | 0.75 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022167867-A1 | SUBSTITUTED CYCLIC MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME | RAPPTA THERAPEUTICS OY (FI) | 2022-08-11 | — | — | WO | disclosed |