Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.83 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.83 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.83 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL3384608 | 1.00 | — | — | |
| Glycine SCHEMBL27836964 | 0.96 | — | — | |
| Glycine SCHEMBL29220903 | 0.96 | — | — | |
| Glycine SCHEMBL474856 | 0.92 | — | — | |
| Glycine SCHEMBL28317820 | 0.92 | — | — | |
| Glycine SCHEMBL6675874 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1FFAR3 | |
| Glycine SCHEMBL93765 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1FFAR3 | |
| Glycine SCHEMBL2116443 | 0.91 | — | — | |
| Glycine SCHEMBL391786 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1FFAR3 | |
| Glycine SCHEMBL3640989 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12004537-B2 | Compositions comprising fabaceae family plant components, processes of preparation and uses thereof | VIRENTIA INNOVATION INC. (CA) | 2024-06-11 | — | — | US | disclosed |
| US-20240133904-A1 | MONOCLONAL ANTIBODY AGAINST D-DIMER AND DIAGNOSIS AGENT FOR DETECTING D-DIMER, CROSSLINKED FIBRIN AND ITS DERIVATIVES CONTAINING D-DIMER BY USING THE ANTIBODY | PRINCETON BIOMEDITECH CORPORATION (US) | 2024-04-25 | — | — | US | disclosed |
| WO-2024033684-A1 | COMPOSITIONS, METHODS AND USES OF EXTRACELLULAR VESICLES OF GIARDIA SPP | UNIVERSIDADE DE COIMBRA (PT) | 2024-02-15 | — | — | WO | disclosed |
| US-20240000107-A1 | COMPOSITIONS COMPRISING FABACEAE FAMILY PLANT COMPONENTS, PROCESSES OF PREPARATION AND USES THEREOF | VIRENTIA INNOVATION INC. (CA) | 2024-01-04 | — | — | US | disclosed |
| CN-116769019-B | ASFVp30 protein monoclonal antibody and application thereof | 河北农业大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115029351-B | Application of shRNA or BACH 1-deleted macrophage-derived EVs in preparation of medicine for treating hypertension | 江南大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116769019-A | ASFVp30 protein monoclonal antibody and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | disclosed |
| US-11578108-B2 | Amphiphysin-I mutant having anti-senescence activity and use thereof | Chungbuk National University Industrial-Academic Cooperation Foundation (KR) | 2023-02-14 | — | — | US | disclosed |
| CN-115029351-A | Application of shRNA or BACH1 deletion macrophage-derived EVs in preparation of medicine for treating hypertension | 江南大学 | 2022-09-09 | — | — | CN | disclosed |
| US-20210093693-A1 | NOVEL USE OF GIT HAVING ANTI-SENESCENCE ACTIVITY | CHUNGBUK NATIONAL UNIVERSITY INDUSTRY - ACADEMIC COOPERATION FOUNDATION (KR) | 2021-04-01 | — | — | US | disclosed |
| US-5510241-A | USING MONOCLONAL ANTIBODIES | THE MINISTER OF AGRICULTURE, FISHERIES AND FOOD IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITIAN AND NORTHERN IRELAND (GB) | 1996-04-23 | — | — | US | disclosed |
| WO-1995032430-A2 | ASSAY FOR PATHOGENICITY OF ANTI-DNA ANTIBODIES | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1995-11-30 | — | — | WO | disclosed |
| WO-1995022611-A2 | METHODS AND COMPOSITIONS FOR STIMULATING BONE CELLS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1995-08-24 | — | — | WO | disclosed |
| EP-0551325-A1 | METHOD OF TESTING FOR SALMONELLA | The Minister of Agriculture, Fisheries & Food in Her Britannic Majesty's Government of the United Kingdom and Northern Ireland (GB) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019133-B | MONOCLONAL ANTIBODIES TO PSEUDOMONAS AERUGINOSA FLAGELLA | GENETIC SYSTEMS CORP (US) | 1992-11-18 | — | — | CN | disclosed |
| WO-1992006197-A1 | METHOD OF TESTING FOR SALMONELLA | THE MINISTER FOR AGRICULTURE, FISHERIES AND FOOD IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1992-04-16 | — | — | WO | disclosed |
| US-4895804-A | IMMUNOLOGY | UNIVERSITY OF MINNESOTA (US) | 1990-01-23 | — | — | US | disclosed |
| US-4834976-A | Monoclonal antibodies to pseudomonas aeruginosa flagella | GENETIC SYSTEMS CORPORATION (US) | 1989-05-30 | — | — | US | disclosed |
| CN-87104581-A | The monoclonal antibody of resisting pseudomonas aeruginosa flagellum | — | 1988-09-21 | — | — | CN | disclosed |
| US-4755460-A | Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle | THE REGENTS OF THE UNIV. OF MINNESOTA (US) | 1988-07-05 | — | — | US | disclosed |