Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 1.00 |
| ▸ | SLC6A9 | P48067 | 1/20 | 1.00 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 1.00 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL30070584 | 1.00 | — | — | |
| Glycine SCHEMBL3640989 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL30179260 | 1.00 | — | — | |
| Glycine SCHEMBL2116443 | 1.00 | — | — | |
| Glycine SCHEMBL6163 | 1.00 | — | — | |
| Glycine SCHEMBL391027 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL13169653 | 1.00 | — | — | |
| Glycine SCHEMBL6675874 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL391786 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL29910347 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 16739 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120082577-A | Method for controlling sgRNA intracellular localization and regulating gene expression | 广州医科大学 | 2025-06-03 | — | — | CN | claimed |
| WO-2025042352-A2 | SINGLE-CHAIN VARIABLE FRAGMENT (SCFV) MOUSE ANTIBODY SPECIFIC TO SAPOSIN-LIKE PROTEIN 2 OF THE LIVER FLUKE FASCIOLA GIGANTICA | BURAPHA UNIVERSITY (TH) | 2025-02-27 | — | — | WO | claimed |
| WO-2024140838-A1 | ANTI-BDCA2 ANTIBODY-DRUG CONJUGATE AND USE THEREOF | 映恩生物制药（苏州）有限公司 | 2024-07-04 | — | — | WO | claimed |
| EP-4393937-A1 | STEROID COMPOUND AND CONJUGATE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2024-07-03 | — | — | EP | claimed |
| CN-117487029-B | Difunctional antibacterial peptide and synthesis method and application thereof | 南昌大学第一附属医院 | 2024-03-12 | — | — | CN | claimed |
| CN-117487029-A | Difunctional antibacterial peptide and synthesis method and application thereof | 南昌大学第一附属医院 | 2024-02-02 | — | — | CN | claimed |
| CN-110546159-B | Parathyroid hormone fusion polypeptides | 谢菲尔德大学 | 2023-08-22 | — | — | CN | claimed |
| WO-2023137026-A1 | CAMPTOTHECIN ANALOGS CONJUGATED TO A GLUTAMINE RESIDUE IN A PROTEIN, AND THEIR USE | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-20 | — | — | WO | claimed |
| EP-4178625-A1 | CAMPTOTHECIN ANALOGS CONJUGATED TO A GLUTAMINE RESIDUE IN A PROTEIN, AND THEIR USE | Regeneron Pharmaceuticals, Inc. (US) | 2023-05-17 | — | — | EP | claimed |
| CN-115925932-A | Antibodies against interleukin 36 receptor (IL-36R) | 安奈普泰斯生物有限公司 | 2023-04-07 | — | — | CN | claimed |
| EP-0514413-A1 | IMMUNOLOGICALLY ACTIVE PEPTIDES OR POLYPEPTIDES FROM THE PARVOVIRUS B19. | MIKROGEN MOLEKULARBIOL ENTW (DE) | 1992-11-25 | — | — | EP | claimed |
| WO-1992010575-A1 | BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION | BIOGEN, INC. (US) | 1992-06-25 | — | — | WO | claimed |
| WO-1991012269-A1 | IMMUNOLOGICALLY ACTIVE PEPTIDES OR POLYPEPTIDES FROM THE PARVOVIRUS B19 | MIKROGEN MOLEKULARBIOLOGISCHE ENTWICKLUNGS-GMBH (DE) | 1991-08-22 | — | — | WO | claimed |
| US-5030240-A | Perhydrolysis; cleaning compounds | THE CLOROX COMPANY (US) | 1991-07-09 | — | — | US | claimed |
| WO-1991007499-A1 | THE SCL GENE, AND THE ENCODED HEMATOPOIETIC FACTOR | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1991-05-30 | — | — | WO | claimed |
| CN-87106313-A | The improvement of organic compound | — | 1988-05-04 | — | — | CN | claimed |
| WO-1988002023-A1 | RECOMBINANT LIGNINASE | SANDOZ AG (CH) | 1988-03-24 | — | — | WO | claimed |
| EP-0190254-A4 | CLONED GENE AND METHOD FOR MAKING AND USING THE SAME. | GENEX CORP (US) | 1987-03-09 | — | — | EP | claimed |
| EP-0190254-A1 | CLONED GENE AND METHOD FOR MAKING AND USING THE SAME | GENEX CORPORATION (US) | 1986-08-13 | — | — | EP | claimed |
| WO-1986000528-A1 | CLONED GENE AND METHOD FOR MAKING AND USING THE SAME | GENEX CORPORATION (US) | 1986-01-30 | — | — | WO | claimed |