Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 1.00 |
| ▸ | SLC6A9 | P48067 | 1/20 | 1.00 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 1.00 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL30070584 | 1.00 | — | — | |
| Glycine SCHEMBL3640989 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL30179260 | 1.00 | — | — | |
| Glycine SCHEMBL2116443 | 1.00 | — | — | |
| Glycine SCHEMBL6163 | 1.00 | — | — | |
| Glycine SCHEMBL391027 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL13169653 | 1.00 | — | — | |
| Glycine SCHEMBL6675874 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL93765 | 1.00 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL29910347 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2030 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111778169-B | Method for improving in vitro protein synthesis efficiency | 康码（上海）生物科技有限公司 | 2023-02-10 | — | — | CN | claimed |
| CN-101165070-B | A series of fusion protein with dual biological activity and medical treatment thereof | BO YU | 2010-12-08 | — | — | CN | claimed |
| CN-1325649-C | Gene recombinant human cytomegalovirus fusion protein pp150/MDBP, preparation process and application thereof | SHANDONG MEDICINAL BIOTECHNOLO (CN) | 2007-07-11 | — | — | CN | claimed |
| EP-1615998-A4 | PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS | BASF PLANT SCIENCE GMBH (DE) | 2007-06-13 | — | — | EP | claimed |
| CN-1763203-A | Gene recombinant human cytomegalovirus fusion protein pp150/MDBP, preparation process and application thereof | SHANDONG MEDICINAL BIOTECHNOLO (CN) | 2006-04-26 | — | — | CN | claimed |
| EP-1615998-A2 | PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS | BASF Plant Science GmbH (DE) | 2006-01-18 | — | — | EP | claimed |
| WO-2004092349-A2 | PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS | BASF PLANT SCIENCE GMBH (DE) | 2004-10-28 | — | — | WO | claimed |
| EP-1379658-A2 | ANTIMICROBIAL PEPTIDES AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2004-01-14 | — | — | EP | claimed |
| EP-1307479-A2 | HERBICIDE TARGET GENES AND METHODS | Syngenta Participations AG (CH) | 2003-05-07 | — | — | EP | claimed |
| WO-2001070980-A9 | ISOLATED G-PROTEIN COUPLED RECEPTORS, NUCLEIC ACID MOLECULES ENCODING GPCR PROTEINS, AND USES THEREOF AS INSECTICIDAL TARGETS | PE CORP NY (US) | 2003-01-16 | — | — | WO | claimed |
| WO-2002026246-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING POLYNUCLEOTIDES ENCODING A RAF PROTEIN | GSF-FORSCHUNGSZENTRUM FÜR UMWELT UND GESUNDHEIT, GMBH (DE) | 2002-04-04 | — | — | WO | claimed |
| WO-2002022821-A2 | ANTIMICROBIAL PEPTIDES AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| US-6355462-B1 | NUCLEOTIDE SEQUENCES CODING ENZYMATIC POLYPEPTIDE FOR USE IN THE GENERATION OF DISEASE RESISTANT PLANTS | E.I. DU PONT DE NEMOURS AND COMPANY | 2002-03-12 | — | — | US | claimed |
| WO-2002000696-A2 | HERBICIDE TARGET GENES AND METHODS | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-03 | — | — | WO | claimed |
| US-5717065-A | Synthetic polypeptides and antibodies related to epstein-barr virus nuclear antigen | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-02-10 | — | — | US | claimed |
| CN-115038722-B | Antibodies against KLK5 | UCB biopharmaceutical Co.,Ltd. (BE) | 2026-05-26 | — | — | CN | disclosed |
| CN-122070138-A | Compositions and methods for expressing EGFR | 瑞普利科特生物科学公司 | 2026-05-19 | — | — | CN | disclosed |
| WO-1990015153-A1 | A METHOD FOR THE DETECTION OF ANTI-STREPTOKINASE ANTIBODIES | GEORGETOWN UNIVERSITY (US) | 1990-12-13 | — | — | WO | disclosed |
| WO-1988008164-A1 | COMPUTER DESIGNED STABILIZED PROTEINS AND METHOD FOR PRODUCING SAME | GENEX CORPORATION (US) | 1988-10-20 | — | — | WO | disclosed |
| WO-1988008165-A1 | COMPUTER BASED METHOD FOR PROTEIN ENGINEERING | GENEX CORPORATION (US) | 1988-10-20 | — | — | WO | disclosed |