Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24390007 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 | |
| SCHEMBL29988431 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 | |
| SCHEMBL30132807 | 1.00 | ALDH1A1 (0.41) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 | |
| SCHEMBL25315194 | 0.88 | PGR (0.39) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 | |
| SCHEMBL25311778 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL30132777 | 0.85 | NR3C2 (0.32) | ALDH1A1 | |
| SCHEMBL25314375 | 0.85 | NR3C2 (0.32) | ALDH1A1 | |
| SCHEMBL25317864 | 0.85 | MEN1 (0.36) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 | |
| SCHEMBL25311862 | 0.84 | ALDH1A1 (0.47) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 | |
| SCHEMBL30132788 | 0.84 | ALDH1A1 (0.47) | ALDH1A1ITGB2ICAM1ITGALCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022215034-A1 | INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE | RHIZEN PHARMACEUTICALS AG (CH) | 2022-10-13 | — | — | WO | disclosed |