Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 3/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2076056 | 1.00 | KMO (0.54) | KMOL3MBTL1HRH4PI4KAPI4K2B | |
| SCHEMBL30566910 | 0.98 | KMO (0.51) | KMOL3MBTL1HRH4PI4KAPI4K2B | |
| SCHEMBL25369779 | 0.98 | KMO (0.51) | KMOL3MBTL1HRH4PI4KAPI4K2B | |
| SCHEMBL17891983 | 0.94 | KMO (0.47) | KMOL3MBTL1HRH4PI4KAPI4K2B | |
| SCHEMBL6119719 | 0.90 | KMO (0.42) | KMOPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL31000813 | 0.85 | KMO (0.63) | KMOL3MBTL1HRH4PI4KAPI4K2B | |
| Formic Acid SCHEMBL28591621 | 0.84 | KMO (0.47) | KMOL3MBTL1HRH4PI4KAPI4K2B | |
| SCHEMBL23025135 | 0.81 | RET (0.38) | KMOCSF1RASIC3RETCA2 | |
| Formic Acid SCHEMBL27917749 | 0.79 | KMO (0.42) | KMOADORA2AASIC3ALOX5APFEN1 | |
| SCHEMBL25178766 | 0.74 | RET (0.34) | KMOASIC3RAB9ARETCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256075-A1 | PYRIMIDINE AND PYRIDINE AMINE COMPOUNDS AND USAGE THEREOF IN DISEASE TREATMENT | EPIGEN BIOSCIENCES, INC. (US) | 2022-12-08 | — | — | WO | disclosed |