Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 3/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566910 | 0.96 | KMO (0.51) | KMOALOX5APFEN1ADORA2AADORA3 | |
| SCHEMBL25369779 | 0.96 | KMO (0.51) | KMOALOX5APFEN1ADORA2AADORA3 | |
| SCHEMBL2076056 | 0.94 | KMO (0.54) | KMOALOX5APFEN1ADORA2AADORA3 | |
| SCHEMBL24692153 | 0.94 | KMO (0.54) | KMOALOX5APFEN1ADORA2AADORA3 | |
| SCHEMBL6119719 | 0.91 | KMO (0.42) | KMOALOX5APFEN1ADORA2AADORA3 | |
| Formic Acid SCHEMBL28591621 | 0.89 | KMO (0.47) | KMOALOX5APFEN1ADORA2AADORA3 | |
| SCHEMBL23025135 | 0.82 | RET (0.38) | KMOASIC3CA2CHKARET | |
| Formic Acid SCHEMBL27917749 | 0.81 | KMO (0.42) | KMOALOX5APFEN1ADORA2AASIC3 | |
| SCHEMBL31000813 | 0.78 | KMO (0.63) | KMOADORA2AHRH4PI4KAPI4K2B | |
| SCHEMBL25178766 | 0.76 | RET (0.34) | KMOASIC3CA2CHKARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108612-B | Pesticidally active tetracyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2020-05-15 | — | — | CN | disclosed |
| US-10196398-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-05 | — | — | US | disclosed |
| US-20180009813-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-11 | — | — | US | disclosed |
| EP-3240788-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2017-11-08 | — | — | EP | disclosed |
| CN-107108612-A | The active tetracyclic of harmful organism is killed with sulfur-bearing substituent | 先正达参股股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016107742-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009813-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, GSTO1 | KMO 544/4885ALOX5AP 1893/4885FEN1 1880/4885 |
| US-10196398-B2 | Pesticidally active tetracyclic derivatives with sulfur containing substituents | DDT, TST, GSTO1 | KMO 544/4885ALOX5AP 1893/4885FEN1 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.