Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.90 |
| ▸ | MPO | P05164 | 9/20 | 0.82 |
| ▸ | HTR1D | P28221 | 4/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.67 |
| ▸ | HTR1B | P28222 | 2/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 1/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.67 |
| ▸ | HTR2C | P28335 | 1/20 | 0.67 |
| ▸ | HTR1E | P28566 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | HTR5A | P47898 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30053751 | 1.00 | HTR2A (0.90) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL24694055 | 0.95 | HTR2A (0.81) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL24243711 | 0.94 | HTR2A (1.00) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL30054225 | 0.94 | HTR2A (1.00) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| Hydrochloric Acid SCHEMBL29765862 | 0.93 | HTR2A (1.00) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL29206531 | 0.90 | HTR2A (0.82) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL30916160 | 0.90 | MPO (1.00) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL24692678 | 0.89 | HTR2A (0.84) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL29206551 | 0.88 | HTR2A (0.78) | HTR2AMPOHTR1DSLC6A4HTR1A | |
| SCHEMBL2405100 | 0.88 | HTR2A (0.74) | HTR2AMPOHTR1DSLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117957211-A | Fluorinated tryptamine compounds, analogs thereof, and methods of use thereof | 圣约瑟夫大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2022256554-A1 | FLUORINATED TRYPTAMINE COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | UNIVERSITY OF THE SCIENCES (US) | 2022-12-08 | — | — | WO | disclosed |