Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | STK10 | O94804 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | YES1 | P07947 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427330 | 0.76 | KDR (0.69) | KDRABCB1FLT1CITMAP3K7 | |
| SCHEMBL1715372 | 0.74 | KDR (0.65) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL25945416 | 0.74 | KDR (0.56) | KDRABCB1FLT1CITMAP3K7 | |
| SCHEMBL6542710 | 0.74 | KDR (0.62) | KDRALDH1A1 | |
| SCHEMBL3413933 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTHDAC1HDAC6 | |
| SCHEMBL30595572 | 0.73 | KDR (0.62) | KDRALDH1A1ABCB1MAP4K4RET | |
| SCHEMBL5261234 | 0.73 | KDR (0.62) | KDRALDH1A1ABCB1MAP4K4RET | |
| SCHEMBL8570752 | 0.73 | P2RX7 (0.47) | ALDH1A1GAAMAPT | |
| SCHEMBL9753927 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1GAAMAPTEGFR | |
| SCHEMBL28236466 | 0.71 | KDR (0.62) | KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022254255-A1 | NEURO-MESENCHYME UNITS CONTROL ILC2 AND OBESITY VIA A BRAIN-ADIPOSE CIRCUIT | FUNDACAO D. ANNA DE SOMMERCHAMPALIMAUD E DR. (PT) | 2022-12-08 | — | — | WO | disclosed |