Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 9/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24694020 | 0.91 | HCRTR1 (0.35) | HCRTR1HCRTR2HTR1AHTR2AHTR7 | |
| SCHEMBL24693510 | 0.85 | HCRTR1 (0.35) | HCRTR1HCRTR2HTR1AHTR2AHTR7 | |
| SCHEMBL24694358 | 0.85 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL24693092 | 0.83 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL24693295 | 0.83 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL24694374 | 0.82 | HCRTR1 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL24693511 | 0.82 | HCRTR1 (0.33) | HCRTR1HCRTR2HTR1AHTR2AHTR7 | |
| SCHEMBL24693052 | 0.82 | SLC6A4 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL25936104 | 0.82 | MEN1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL25936106 | 0.81 | HCRTR1 (0.34) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253167-A1 | SUBSTITUTED PHENYL-1H-PYRROLO [2, 3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2022-12-08 | — | — | WO | disclosed |