Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24694020 | 0.91 | HCRTR1 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL24693513 | 0.89 | HCRTR1 (0.39) | MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL24694023 | 0.85 | MYC (0.35) | — | |
| SCHEMBL24693512 | 0.84 | PDE4A (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL24694759 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2A | |
| SCHEMBL19972556 | 0.83 | KDM4C (0.33) | MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL24693284 | 0.82 | HCRTR1 (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL24693511 | 0.80 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL25936106 | 0.80 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL24693302 | 0.78 | SLC6A2 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-10 | — | — | US | disclosed |
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250096-A1 | SUBSTITUTED PHENYL-1H-PYRROLO[2,3-c] PYRIDINE DERIVATIVES | MLLT1, BMI1, MEN1 | MEN1 3/4885KMT2A 198/4885HCRTR1 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.