SCHEMBL2469353

SCHEMBL2469353

CN(C)c1c(Cl)cc(F)c(-c2cc(N)c(Cl)c(OC(=O)O)n2)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2467547 0.89 NQO2 (0.31)
SCHEMBL17797198 0.85 KMT2A (0.30)
SCHEMBL2471013 0.84 TPMT (0.32)
SCHEMBL3454529 0.84
SCHEMBL17797194 0.84 KDM4E (0.31)
SCHEMBL2469352 0.84 CYP3A4 (0.33)
SCHEMBL2467629 0.83 FFAR4 (0.35) FFAR4
SCHEMBL17797219 0.81 LMNA (0.36) FFAR4
SCHEMBL3324334 0.80 NQO2 (0.36)
SCHEMBL17797241 0.80 TPMT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2060566-B1 Poly-substituted aryls DOW AGROSCIENCES LLC (US) 2016-06-08 EP claimed
EP-2939540-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP disclosed
EP-2939541-A1 HERBICIDE SAFENER COMBINATION Bayer Intellectual Property GmbH (DE) 2015-11-04 EP disclosed
EP-2369929-A2 HERBICIDE-SAFENER COMBINATION Bayer CropScience AG (DE) 2011-10-05 EP disclosed
WO-2010060581-A2 HERBICIDE-SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO disclosed
EP-2191719-A1 Herbicide safener combination Bayer CropScience AG (DE) 2010-06-02 EP disclosed