Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464489 | 0.91 | MET (0.79) | METHDAC1 | |
| Hydrochloric Acid SCHEMBL2672902 | 0.90 | MET (0.78) | METHDAC1 | |
| SCHEMBL4125734 | 0.90 | MET (0.68) | METHDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL3117528 | 0.90 | MET (0.59) | METMEN1KMT2AALDH1A1 | |
| SCHEMBL2470219 | 0.89 | MET (0.62) | METHDAC1MEN1KMT2A | |
| SCHEMBL2672593 | 0.89 | ALDH1A1 (0.59) | METHDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL2469377 | 0.88 | MET (0.66) | METMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2673128 | 0.88 | ALDH1A1 (0.58) | METHDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4126839 | 0.88 | MET (0.86) | METMEN1KMT2A | |
| SCHEMBL2672558 | 0.87 | MET (0.64) | METHDAC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |