Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24695635 | 1.00 | KMO (0.44) | KMOKDM4EALDH1A1HPGDGAA | |
| SCHEMBL20064749 | 0.86 | KMO (0.43) | KMOKDM4EALDH1A1HPGDGAA | |
| SCHEMBL24696226 | 0.86 | HPGD (0.59) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24695637 | 0.86 | HPGD (0.42) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24695810 | 0.86 | HPGD (0.42) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24696384 | 0.82 | P2RY14 (0.37) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24696143 | 0.82 | P2RY14 (0.37) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24695982 | 0.81 | HPGD (0.48) | KMOKDM4EALDH1A1HPGDGAA | |
| SCHEMBL24696341 | 0.81 | KDM4E (0.37) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24696319 | 0.80 | HPGD (0.52) | KMOKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | disclosed |