SCHEMBL2469609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2470733	0.89	ELOVL6 (0.42)	MAPTPKMELOVL6CYP46A1HTR2A
	SCHEMBL2470730	0.86	ELOVL6 (0.42)	MAPTPKMELOVL6CYP46A1HTR2A
	SCHEMBL2474367	0.83	MDM2 (0.41)	MAPTELOVL6PDK2IDO1
	SCHEMBL2471501	0.82	CYP46A1 (0.38)	MAPTELOVL6CYP46A1HTR2AMGAM
	SCHEMBL2472692	0.81	MAPT (0.37)	MAPTELOVL6CYP46A1HTR2AMGAM
	SCHEMBL13087801	0.81	MAPT (0.36)	MAPTELOVL6CYP46A1HTR2AAKR1B1
	SCHEMBL2471643	0.81	CYP46A1 (0.39)	MAPTELOVL6CYP46A1HTR7AKR1B1
	SCHEMBL2467594	0.81	CYP46A1 (0.38)	MAPTELOVL6CYP46A1HTR2AAKR1B1
	SCHEMBL2467447	0.81	MAPT (0.36)	MAPTELOVL6CYP46A1HTR2AMGAM
	SCHEMBL2470308	0.81	MAPT (0.36)	MAPTELOVL6CYP46A1HTR2AMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.