SCHEMBL24696290

SCHEMBL24696290

c1ccc(-c2ccc(-c3nc(-c4ccc5c6ccccc6n(-c6ccccc6)c5c4)nc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccccc7)c6c54)n3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 2/20 0.45
KDM4E B2RXH2 1/20 0.45
AVPR1A P37288 1/20 0.38
KMT2A Q03164 6/20 0.34
MEN1 O00255 5/20 0.34
MAPT P10636 3/20 0.34
HSP90AA1 P07900 1/20 0.34
IL1R1 P14778 1/20 0.34
HDAC4 P56524 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
PTGER4 P35408 1/20 0.33
MAPK1 P28482 1/20 0.33
PRMT5 O14744 1/20 0.32
MAT2A P31153 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26412975 0.99 L3MBTL1 (0.44) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL24800681 0.99 L3MBTL1 (0.46) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26054154 0.97 L3MBTL1 (0.45) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL27050502 0.96 KDM4E (0.42) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL24696286 0.95 KDM4E (0.41) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26055053 0.95 L3MBTL1 (0.43) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26628240 0.95 KDM4E (0.43) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL26054474 0.95 L3MBTL1 (0.43) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL25473551 0.94 L3MBTL1 (0.40) L3MBTL1ATMKDM4EAVPR1AKMT2A
SCHEMBL25473627 0.94 L3MBTL1 (0.40) L3MBTL1ATMKDM4EAVPR1AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228496-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-07-11 US disclosed
US-20240228496-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-07-11 US disclosed
US-20240237523-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-07-11 US disclosed
US-20240237523-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-07-11 US disclosed
US-20240032322-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20240032322-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-01-25 US disclosed
EP-4276925-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-11-15 EP disclosed
EP-4266392-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR MANUFACTURING SAME NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-10-25 EP disclosed
WO-2022255241-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT 日鉄ケミカル&マテリアル株式会社 2022-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228496-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, WEE2, CTNNA1 L3MBTL1 488/4885ATM 4552/4885KDM4E 1781/4885
US-20240237523-A1 DEUTERIDE AND ORGANIC ELECTROLUMINESCENT ELEMENT LEF1, OR51E2, WEE2 L3MBTL1 633/4885ATM 4378/4885KDM4E 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.