SCHEMBL24697207

SCHEMBL24697207

CNC(=O)C[C@H](I)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.37
MAPT P10636 1/20 0.36
MCL1 Q07820 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.33
SLC6A3 Q01959 1/20 0.32
GABRR1 P24046 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17300185 0.78 GABRR1 (0.41) ATMMAPTMCL1LMNAGABRR1
SCHEMBL9947548 0.78 GABRR1 (0.41) ATMMAPTMCL1LMNAGABRR1
SCHEMBL19352706 0.78 GABRR1 (0.41) ATMMAPTMCL1LMNAGABRR1
SCHEMBL23873825 0.77 MEN1 (0.39) LMNAGABRR1
SCHEMBL27370003 0.74 PSMB5 (0.31)
SCHEMBL7078228 0.73 SMN1; SMN2 (0.52) ATMMAPTMCL1LMNA
SCHEMBL7078226 0.73 SMN1; SMN2 (0.52) ATMMAPTMCL1LMNA
SCHEMBL7078225 0.73 SMN1; SMN2 (0.52) ATMMAPTMCL1LMNA
SCHEMBL8368782 0.71 SLC7A5 (0.50)
SCHEMBL13931455 0.71 RNPEP (0.44) ATMMAPTMCL1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11766481-B2 Glycan modified short interfering RNA GANNA BIO, INC. (US) 2023-09-26 US disclosed
US-20220387607-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11766481-B2 Glycan modified short interfering RNA SNRPE, FUT6, ALG8 ATM 2468/4885MAPT 4586/4885MCL1 4034/4885
US-20220387607-A1 GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES NSUN3, RNGTT, SIGLEC7 ATM 3219/4885MAPT 4153/4885MCL1 2319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.