Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 18/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467247 | 0.95 | MET (0.50) | METTSHRALDH1A1L3MBTL1 | |
| SCHEMBL2469731 | 0.93 | MET (0.54) | METTSHRALDH1A1L3MBTL1 | |
| SCHEMBL1953412 | 0.91 | MET (0.53) | MET | |
| SCHEMBL2470373 | 0.91 | MET (0.43) | METTSHRALDH1A1L3MBTL1USP2 | |
| SCHEMBL2468002 | 0.90 | MET (0.65) | METTSHR | |
| SCHEMBL2472186 | 0.89 | MET (0.52) | MET | |
| SCHEMBL2468076 | 0.88 | MET (0.52) | MET | |
| SCHEMBL2472162 | 0.86 | MET (0.52) | METTSHRALDH1A1L3MBTL1 | |
| SCHEMBL2464470 | 0.85 | MET (0.43) | METTSHRALDH1A1L3MBTL1USP2 | |
| SCHEMBL2466209 | 0.85 | MET (0.46) | METTSHRALDH1A1L3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |