Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6672668 | 0.98 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL11292693 | 0.98 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL2026336 | 0.98 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL6668543 | 0.98 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL6669104 | 0.98 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL28311626 | 0.92 | DNM1 (0.44) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL29281610 | 0.92 | DNM1 (0.44) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL30954840 | 0.92 | DNM1 (0.44) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL15140667 | 0.92 | DNM1 (0.43) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL27870214 | 0.90 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2ATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805037-B1 | DONOR ELEMENT WITH RELEASE-MODIFIER FOR THERMAL TRANSFER | DU PONT (US) | 2011-10-05 | — | — | EP | disclosed |
| EP-1805034-B1 | DONOR ELEMENT FOR THERMAL TRANSFER | DU PONT (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-1802471-B1 | DONOR ELEMENT FOR RADIATION-INDUCED THERMAL TRANSFER | DU PONT (US) | 2010-12-01 | — | — | EP | disclosed |
| US-7763411-B2 | support layer, light-to-heat conversion layer comprising light absorber, transfer layer, and release modifier such as quaternery ammonium compound | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-27 | — | — | US | disclosed |
| US-20090047596-A1 | Donor element with release-modifier for thermal transfer | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-02-19 | — | — | US | disclosed |
| US-20090047597-A1 | Donor element for radiation-induced thermal transfer | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-02-19 | — | — | US | disclosed |
| US-7387864-B2 | Donor element for thermal transfer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-20080090169-A1 | Composite Film Suitable as a Donor Support in a Radiation-Induced Thermal Transfer Imaging Process | DUPONT TEIJIN FILMS U.S. LIMITED PARTNERSHIP (DE) | 2008-04-17 | — | — | US | disclosed |
| US-20080003519-A1 | Donor Element for Thermal Transfer | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-01-03 | — | — | US | disclosed |
| EP-1805034-A1 | DONOR ELEMENT FOR THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006045085-A1 | DONOR ELEMENT FOR THERMAL TRANSFER | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |