Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311626 | 1.00 | DNM1 (0.44) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL29281610 | 1.00 | DNM1 (0.44) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL27870214 | 0.98 | DNM1 (0.42) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL6672668 | 0.94 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL6669104 | 0.94 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL6668543 | 0.94 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL11292693 | 0.94 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL2026336 | 0.94 | DNM1 (0.47) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL2469815 | 0.92 | DNM1 (0.46) | DNM1PSMD14PLA2G1BMMP2ATG4B | |
| SCHEMBL29165751 | 0.92 | RECQL (0.44) | DNM1RAD52RECQLGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114514012-B | External preparation for skin | 株式会社高丝 | 2024-06-14 | — | — | CN | disclosed |