Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 7/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411305 | 0.86 | PAX8 (0.42) | PAX8ALDH1A1EGFRABL1TET2 | |
| SCHEMBL20261884 | 0.79 | ALDH1A1 (0.38) | PAX8ALDH1A1 | |
| SCHEMBL2145697 | 0.77 | ALDH1A1 (0.45) | PAX8ALDH1A1EGFREGLN1TSHR | |
| SCHEMBL2700798 | 0.77 | ALDH1A1 (0.41) | PAX8ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL17929095 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2A | |
| Trimethylammonium SCHEMBL27587058 | 0.76 | ALDH1A1 (0.44) | PAX8ALDH1A1TET2MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL29173774 | 0.76 | ALDH1A1 (0.39) | PAX8ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL20699315 | 0.76 | EGFR (0.39) | PAX8EGFRABL1 | |
| Hydrochloric Acid SCHEMBL5708074 | 0.76 | MEN1 (0.42) | PAX8ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL22034598 | 0.76 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029443-A4 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-09-21 | — | — | EP | claimed |
| EP-0029443-A1 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-06-03 | — | — | EP | claimed |
| WO-1980002687-A1 | PROCESS FOR COMPOSITE POLYMER BEADS | ICI AUSTRALIA LTD (AU) | 1980-12-11 | — | — | WO | claimed |
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-2788000-B1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-30 | — | — | EP | disclosed |
| CN-106471106-A | Variable-speed motor lubricant oil composite | 捷客斯能源株式会社 | 2017-03-01 | — | — | CN | disclosed |
| CN-106414685-A | Lubricating oil composition for differential gear device | 捷客斯能源株式会社 | 2017-02-15 | — | — | CN | disclosed |
| CN-105051071-A | Rubber composition comprising emulsion-polymerized conjugated diene polymer and silica suspension, and process for producing same | ETIC INC | 2015-11-11 | — | — | CN | disclosed |
| US-8993756-B2 | Pyrrolopyrimidines as janus kinase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140349998-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIITORS | MERCK SHARP & DOHME CORP. (US) | 2014-11-27 | — | — | US | disclosed |
| EP-2788000-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-10-15 | — | — | EP | disclosed |
| US-20070191604-A1 | Novel compounds that are ERK inhibitors | SCHERING CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-20070191604-A1 | Novel compounds that are ERK inhibitors | SCHERING CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-20070191604-A1 | Novel compounds that are ERK inhibitors | SCHERING CORPORATION | 2007-08-16 | — | — | US | disclosed |
| WO-2007070398-A1 | POLYCYCLIC INDAZOLE DERIVATIVES THAT ARE ERK INHIBITORS | SCHERING CORPORATION (US) | 2007-06-21 | — | — | WO | disclosed |
| CN-1187764-A | Topical personal care composition containing alkenyl or styrene end-capped silicone grafted copolymer | PROCTER & GAMBLE (US) | 1998-07-15 | — | — | CN | disclosed |
| US-4447475-A | MIXING DISPERSION OF PARTICLES IN CROSSLINKED STYRENE POLYMER MATRIX WITH DISPERSANT AND SUSPENSION STABILIZER | ICI AUSTRALIA LIMITED (AU) | 1984-05-08 | — | — | US | disclosed |
| EP-0029443-A4 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-09-21 | — | — | EP | disclosed |
| EP-0029443-A1 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-06-03 | — | — | EP | disclosed |
| WO-1980002687-A1 | PROCESS FOR COMPOSITE POLYMER BEADS | ICI AUSTRALIA LTD (AU) | 1980-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140349998-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIITORS | JAK3, JAK1, JAK2 | PAX8 4267/4885ALDH1A1 2206/4885EGFR 1095/4885 |
| US-20070191604-A1 | Novel compounds that are ERK inhibitors | MAPK1, MAPK4, MAPKAPK2 | PAX8 4742/4885ALDH1A1 342/4885EGFR 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.