Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 3/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24697981 | 0.92 | PIK3R1 (0.36) | HMOX1CA4POLBEHMT2LMNA | |
| SCHEMBL24699240 | 0.89 | MTOR (0.35) | MTOR | |
| SCHEMBL30015790 | 0.87 | MTOR (0.32) | POLBEHMT2LMNACA12CA2 | |
| SCHEMBL24698640 | 0.87 | MTOR (0.32) | POLBEHMT2LMNACA12CA2 | |
| SCHEMBL24699603 | 0.86 | BRD4 (0.37) | CA4POLBEHMT2CA12CA1 | |
| SCHEMBL30016531 | 0.84 | PI4KB (0.36) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL24697976 | 0.84 | PI4KB (0.36) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL24699229 | 0.84 | MTOR (0.36) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL30016058 | 0.84 | MTOR (0.36) | LMNAPDK1PDK2PDK3PDK4 | |
| SCHEMBL24699069 | 0.83 | PI4KB (0.35) | POLBPDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |