Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 4/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016077 | 1.00 | ACACB (0.41) | ACACBACACAMTORUSP30SUCNR1 | |
| SCHEMBL24699348 | 0.88 | SUCNR1 (0.41) | ACACBACACAUSP30SUCNR1NPC1 | |
| SCHEMBL30016523 | 0.88 | MTOR (0.42) | MTORNPC1RAB9ASYKPIK3R1 | |
| SCHEMBL24698892 | 0.88 | MTOR (0.48) | MTORNPC1RAB9ASYKSMYD2 | |
| SCHEMBL24697628 | 0.88 | MTOR (0.42) | MTORNPC1RAB9ASYKPIK3CA | |
| SCHEMBL30016136 | 0.87 | ROCK2 (0.43) | ACACBACACAMTORNAMPTCKS1B | |
| SCHEMBL29134944 | 0.87 | ROCK2 (0.43) | ACACBACACAMTORNAMPTCKS1B | |
| SCHEMBL24698512 | 0.87 | ROCK2 (0.43) | ACACBACACAMTORNAMPTCKS1B | |
| SCHEMBL24697681 | 0.87 | HRH3 (0.42) | MTORNPC1RAB9ASYKSMYD2 | |
| SCHEMBL30017041 | 0.87 | HRH3 (0.42) | MTORNPC1RAB9ASYKSMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |