Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 2/20 | 0.37 |
| ▸ | SKP1 | P63208 | 2/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016077 | 0.88 | ACACB (0.41) | SUCNR1PIK3CAACACBACACAGABRA5 | |
| SCHEMBL24699345 | 0.88 | ACACB (0.41) | SUCNR1PIK3CAACACBACACAGABRA5 | |
| SCHEMBL24697994 | 0.87 | PIK3CA (0.45) | PIK3CANPC1RAB9AGBA1SMYD2 | |
| SCHEMBL24698899 | 0.86 | PRKD1 (0.42) | PIK3CANPC1RAB9ASMYD2 | |
| SCHEMBL24698513 | 0.86 | ROCK2 (0.42) | NAMPTCKS1BSKP1SKP2BCHE | |
| SCHEMBL24697633 | 0.86 | PIK3CA (0.41) | PIK3CANPC1RAB9AGBA1SMYD2 | |
| SCHEMBL24697549 | 0.82 | PIK3CA (0.54) | PIK3CAGBA1 | |
| SCHEMBL24698823 | 0.79 | USP30 (0.44) | PIK3CANPC1RAB9AUSP30CKS1B | |
| SCHEMBL24698499 | 0.78 | NPC1 (0.44) | PIK3CANPC1RAB9A | |
| SCHEMBL19623572 | 0.77 | PIK3CA (0.49) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |