Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.76 |
| ▸ | PARP11 | Q9NR21 | 9/20 | 0.76 |
| ▸ | PARP1 | P09874 | 2/20 | 0.57 |
| ▸ | TDP2 | O95551 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 4/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1002712 | 0.86 | PARP10 (1.00) | PARP10PARP11PARP1TDP2GRM5 | |
| SCHEMBL4899191 | 0.80 | PARP10 (0.56) | PARP10PARP11PARP1TDP2PNMT | |
| SCHEMBL17797572 | 0.77 | PARP10 (0.81) | PARP10PARP11PARP1TDP2GRM5 | |
| SCHEMBL29676851 | 0.73 | PARP10 (1.00) | PARP10PARP11PARP1TDP2GRM5 | |
| SCHEMBL13512608 | 0.73 | PARP10 (0.64) | PARP10PARP11PARP1TDP2PNMT | |
| SCHEMBL123731 | 0.73 | PARP10 (1.00) | PARP10PARP11PARP1TDP2GRM5 | |
| SCHEMBL2616889 | 0.73 | PARP10 (0.64) | PARP10PARP11PARP1TDP2PNMT | |
| SCHEMBL3563577 | 0.73 | TDP2 (1.00) | PARP10PARP11TDP2METAP1 | |
| SCHEMBL275805 | 0.72 | PARP10 (0.68) | PARP10PARP11PARP1TDP2GRM5 | |
| SCHEMBL30573213 | 0.69 | PARP10 (0.59) | PARP10PARP11PARP1TDP2PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |