Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.56 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429197 | 0.82 | PDE3B (0.58) | PARP10PARP11PARP1BRD4PNMT | |
| SCHEMBL10815 | 0.81 | DRD2 (0.59) | PARP10PARP11PARP1BRD4PNMT | |
| SCHEMBL24699354 | 0.80 | PARP10 (0.76) | PARP10PARP11PARP1PNMTASIC3 | |
| Hydrochloric Acid SCHEMBL31432826 | 0.80 | DRD2 (0.57) | PARP10PARP11PARP1BRD4PNMT | |
| SCHEMBL6371439 | 0.79 | CA9 (0.45) | PARP10PARP11PARP1CA12CA1 | |
| SCHEMBL17461314 | 0.79 | AHR (0.54) | PARP10PARP11PARP1PNMTCA12 | |
| SCHEMBL7214466 | 0.77 | BRD4 (0.52) | PARP10PARP11PARP1BRD4PNMT | |
| SCHEMBL99208 | 0.77 | MAOA (0.56) | BRD4CA9CMA1AHRPDE3B | |
| Methylamine SCHEMBL27630838 | 0.77 | DRD2 (0.53) | PARP10PARP11PARP1BRD4PNMT | |
| Acetaldehyde SCHEMBL27858363 | 0.76 | PARP10 (0.51) | PARP10PARP11PARP1BRD4PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | PARP10 1511/4885PARP11 829/4885PARP1 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.