Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016511 | 1.00 | MEN1 (0.31) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30016142 | 1.00 | MEN1 (0.31) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30015509 | 0.83 | MEN1 (0.38) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30016653 | 0.83 | MEN1 (0.38) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL24698449 | 0.83 | MEN1 (0.38) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30015676 | 0.83 | MEN1 (0.38) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL24699135 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL30016121 | 0.82 | ALDH1A1 (0.40) | MEN1KMT2APDK1PDK2PDK3 | |
| SCHEMBL24698381 | 0.82 | MTOR (0.41) | HRH3 | |
| SCHEMBL29134822 | 0.82 | MTOR (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212194-A1 | KHK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2022-10-06 | — | — | WO | disclosed |