Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17129839 | 1.00 | POLRMT (0.52) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL24699828 | 0.93 | POLRMT (0.50) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL24699895 | 0.93 | POLRMT (0.50) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL15682895 | 0.89 | POLRMT (0.55) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL17129824 | 0.89 | P2RX1 (0.43) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL17124611 | 0.88 | P2RY2 (0.42) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL13519829 | 0.88 | POLRMT (0.55) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL3699139 | 0.88 | POLRMT (0.55) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL16710862 | 0.88 | POLRMT (0.55) | POLRMTP2RX1P2RX3P2RX4RNASEL | |
| SCHEMBL10149537 | 0.87 | POLRMT (0.56) | POLRMTP2RX1P2RX3P2RX4RNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909209-B1 | 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME LLC (US) | 2022-08-03 | — | — | EP | disclosed |