Fluoride

Fluoride

SCHEMBL2469992

F.O=C(O)C1(F)CC2C=CC1C2

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13526016 0.98 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL2469986 0.82 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL13525791 0.81 CYP2D6 (0.38) CYP2D6CYP2C19
SCHEMBL13525792 0.77 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL9079943 0.74 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL6429482 0.74 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL13525991 0.73 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL8732519 0.72 CYP2D6 (0.36) CYP2D6CYP2C19
SCHEMBL12191694 0.71 P2RX7 (0.41) CYP2D6CYP2C19
SCHEMBL5423530 0.71 P2RX7 (0.41) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1548062-B1 OPTICAL MATERIAL CONTAINING PHOTOCURABLE FLUOROPOLYMER AND PHOTOCURABLE FLUORORESIN COMPOSITION DAIKIN IND LTD (JP) 2011-10-05 EP disclosed
US-20050265685-A1 Optical material containing photocurable fluoropolymer and photocurable fluororesin composition DAIKIN INDUSTRIES, LTD (JP) 2005-12-01 US disclosed
EP-1548062-A1 OPTICAL MATERIAL CONTAINING PHOTOCURABLE FLUOROPOLYMER AND PHOTOCURABLE FLUORORESIN COMPOSITION Daikin Industries, Ltd. (JP) 2005-06-29 EP disclosed