SCHEMBL2469986

SCHEMBL2469986

O=C(F)C1(F)CC2C=CC1C2

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13526016 0.84 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL13525791 0.82 CYP2D6 (0.38) CYP2D6CYP2C19
Fluoride SCHEMBL2469992 0.82 CYP2D6 (0.34) CYP2D6CYP2C19
SCHEMBL13525991 0.74 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL200374 0.69
SCHEMBL3901853 0.68 P2RX7 (0.41) CYP2D6CYP2C19
SCHEMBL9079943 0.67 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL13525855 0.66
SCHEMBL4373203 0.66 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL19381628 0.65 P2RX7 (0.42) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1415974-B1 PROCESS FOR PRODUCTION OF FLUORINE-CONTAINING NORBORNENE DERIVATIVES DAIKIN IND LTD (JP) 2017-03-01 EP disclosed
EP-1548062-B1 OPTICAL MATERIAL CONTAINING PHOTOCURABLE FLUOROPOLYMER AND PHOTOCURABLE FLUORORESIN COMPOSITION DAIKIN IND LTD (JP) 2011-10-05 EP disclosed
US-7649118-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2010-01-19 US disclosed
US-20070129576-A1 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. 2007-06-07 US disclosed
US-20070129576-A1 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. 2007-06-07 US disclosed
US-7186773-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-7186773-B2 Process for preparing fluorine-containing norbornene derivative DAIKIN INDUSTRIES, LTD. (JP) 2007-03-06 US disclosed
US-20050265685-A1 Optical material containing photocurable fluoropolymer and photocurable fluororesin composition DAIKIN INDUSTRIES, LTD (JP) 2005-12-01 US disclosed
EP-1548062-A1 OPTICAL MATERIAL CONTAINING PHOTOCURABLE FLUOROPOLYMER AND PHOTOCURABLE FLUORORESIN COMPOSITION Daikin Industries, Ltd. (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129576-A1 Process for preparing fluorine-containing norbornene derivative ADH1A, FLNA, FFAR2 CYP2D6 1459/4885CYP2C19 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.