Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.31 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469351 | 0.94 | PTGES (0.35) | PTGESMAPK9MAPK8MAPK10MAPK1 | |
| SCHEMBL2466895 | 0.90 | MAPK9 (0.38) | ALOX5APFEN1PTGESMAPK9MAPK8 | |
| SCHEMBL2465877 | 0.90 | ALOX5AP (0.39) | ALOX5APFEN1PTGESFFAR4 | |
| SCHEMBL2469695 | 0.89 | ALOX5AP (0.36) | ALOX5APFEN1PTGESMAPK9MAPK8 | |
| SCHEMBL2466455 | 0.89 | ALOX5AP (0.36) | ALOX5APFEN1PTGESMAPK9MAPK8 | |
| SCHEMBL2468807 | 0.89 | MEP1B (0.36) | ALOX5APFEN1KDM4ECD274PDCD1LG2 | |
| SCHEMBL2465145 | 0.88 | CNR1 (0.37) | ALOX5APFEN1MAPK9MAPK8MAPK10 | |
| SCHEMBL2468405 | 0.87 | PTGES (0.34) | ALOX5APFEN1PTGESMAPK9MAPK8 | |
| SCHEMBL3329184 | 0.85 | ALOX5AP (0.36) | ALOX5APFEN1PTGESSCN9AAPP | |
| SCHEMBL2464652 | 0.84 | SCN10A (0.32) | MAPK9MAPK8MAPK10SCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |
| EP-2939541-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2939540-A1 | HERBICIDE SAFENER COMBINATION | Bayer Intellectual Property GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |
| EP-2369929-A2 | HERBICIDE-SAFENER COMBINATION | Bayer CropScience AG (DE) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010060581-A2 | HERBICIDE-SAFENER COMBINATION | BAYER CROPSCIENCE AG (DE) | 2010-06-03 | — | — | WO | disclosed |
| EP-2191719-A1 | Herbicide safener combination | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |