Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24701301 | 0.85 | HRH1 (0.63) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL19243567 | 0.85 | HRH1 (0.63) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL24701004 | 0.85 | HRH1 (0.63) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL24701104 | 0.76 | HTR6 (0.56) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL28897283 | 0.76 | HRH1 (0.63) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL8807380 | 0.75 | HRH1 (0.62) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL24701101 | 0.72 | SOS1 (0.68) | HRH1ALDH1A1HSD17B10CYP2A6CYP2E1 | |
| SCHEMBL19676412 | 0.70 | HRH1 (0.48) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL24701134 | 0.70 | CYP2A6 (0.72) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 | |
| SCHEMBL24700851 | 0.70 | CYP2A6 (0.72) | HRH1ALDH1A1HSD17B10KDM4ECYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281860-A1 | COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES | ARRAKIS THERAPEUTICS, INC. | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281860-A1 | COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES | NSUN3, NSUN2, POLRMT | HRH1 3727/4885ALDH1A1 2596/4885HSD17B10 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.