SCHEMBL24701633

SCHEMBL24701633

c1ccc2c(c1)sc1c2ccc2c3ccc4c5ccccc5sc4c3[nH]c21

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.63
RAB9A P51151 3/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
GPR3 P46089 1/20 0.52
ERCC5 P28715 1/20 0.47
FEN1 P39748 1/20 0.47
TNKS O95271 2/20 0.47
TNKS2 Q9H2K2 2/20 0.47
ALDH1A1 P00352 4/20 0.42
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 3/20 0.40
HCRTR1 O43613 1/20 0.40
HTT P42858 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX5 P09917 1/20 0.40
MAP3K9 P80192 3/20 0.40
MAP3K11 Q16584 3/20 0.40
CDK4 P11802 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15127089 0.89 MAPT (0.53) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL2603640 0.89 RAB9A (0.53) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL29470201 0.89 MEN1 (0.77) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL2603638 0.89 MEN1 (0.77) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL23098904 0.88 MAPT (0.51) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL18647351 0.86 MEN1 (0.53) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL18774624 0.85 MAPT (0.70) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL21564029 0.84 MAPT (0.51) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL24722903 0.84 ALOX5 (0.50) MAPTRAB9AMEN1KMT2AGPR3
SCHEMBL19382764 0.83 MAPT (0.58) MAPTRAB9AMEN1KMT2AGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022260119-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed
US-20220388991-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388991-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE LSM12, TCF12, OR10J3 MAPT 2890/4885RAB9A 1167/4885MEN1 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.