SCHEMBL24701682

SCHEMBL24701682

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)nc(-c3ccccc3)c3cc(-c5ccccc5)c5ccccc5c34)n2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
ATM Q13315 1/20 0.48
WHR1 P49842 1/20 0.45
ACACA Q13085 2/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
NUDT1 P36639 3/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 2/20 0.36
ADORA2A P29274 1/20 0.36
ALDH1A1 P00352 1/20 0.36
DHFR P00374 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
PSMB5 P28074 1/20 0.35
GAA P10253 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PDE5A O76074 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17035002 0.93 MEN1 (0.55) MEN1KMT2AATMWHR1ACACA
SCHEMBL18200333 0.93 MEN1 (0.55) MEN1KMT2AATMWHR1ACACA
SCHEMBL17034906 0.93 MEN1 (0.55) MEN1KMT2AATMWHR1ACACA
SCHEMBL24701869 0.92 ACACA (0.43) MEN1KMT2AATMWHR1ACACA
SCHEMBL24701687 0.91 MEN1 (0.43) MEN1KMT2AATMWHR1ACACA
SCHEMBL17035152 0.91 ABCG2 (0.43) MEN1KMT2AATMWHR1MAPT
SCHEMBL18201258 0.89 MEN1 (0.48) MEN1KMT2AATMWHR1ACACA
SCHEMBL18200332 0.89 MEN1 (0.51) MEN1KMT2AATMWHR1ACACA
SCHEMBL17035001 0.88 MEN1 (0.48) MEN1KMT2AATMWHR1ACACA
SCHEMBL24701681 0.88 MEN1 (0.47) MEN1KMT2AATMWHR1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220399504-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-15 US disclosed