SCHEMBL24701869

SCHEMBL24701869

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)nc(-c3ccccc3)c3cc(-c5ccccc5)c5ccccc5c34)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 4/20 0.43
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
ALDH1A1 P00352 6/20 0.41
MAPT P10636 6/20 0.41
HPGD P15428 5/20 0.41
NTSR1 P30989 1/20 0.41
WHR1 P49842 1/20 0.40
ATM Q13315 1/20 0.40
KDM4E B2RXH2 5/20 0.39
LMNA P02545 3/20 0.39
MAPK1 P28482 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ELANE P08246 1/20 0.38
DHFR P00374 1/20 0.38
ACHE P22303 1/20 0.37
GLA P06280 1/20 0.37
RECQL P46063 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24701687 0.96 MEN1 (0.43) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL18201121 0.92 ACACA (0.48) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL24701682 0.92 MEN1 (0.48) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL24701868 0.88 MEN1 (0.41) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL20967953 0.86 TOP1 (0.47) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL17035002 0.85 MEN1 (0.55) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL17034906 0.85 MEN1 (0.55) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL18200333 0.85 MEN1 (0.55) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL17034956 0.85 ACHE (0.45) ACACAMEN1KMT2AALDH1A1MAPT
SCHEMBL24701688 0.85 MEN1 (0.44) ACACAMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220399504-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-12-15 US disclosed