Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEL | Q05823 | 4/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.47 |
| ▸ | FHIT | P49789 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470251 | 0.91 | RNASEL (0.51) | RNASELP2RY2FHITADORA1SMN1; SMN2 | |
| SCHEMBL2470239 | 0.91 | RNASEL (0.51) | RNASELP2RY2FHITADORA1SMN1; SMN2 | |
| SCHEMBL2470248 | 0.91 | RNASEL (0.51) | RNASELP2RY2FHITADORA1SMN1; SMN2 | |
| SCHEMBL16495067 | 0.82 | SLC28A1 (0.45) | P2RY2SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18259721 | 0.79 | P2RY12 (0.41) | RNASELP2RY2ADORA1ADORA3ADORA2A | |
| SCHEMBL18259722 | 0.79 | P2RY12 (0.41) | RNASELP2RY2ADORA1ADORA3ADORA2A | |
| SCHEMBL7150959 | 0.77 | RNASEL (0.60) | RNASELP2RY2ADORA1SMN1; SMN2DNPH1 | |
| SCHEMBL29403525 | 0.76 | RNASEL (0.67) | RNASELP2RY2ADORA1SMN1; SMN2DNPH1 | |
| Adenosine SCHEMBL8351411 | 0.76 | ADORA3 (0.74) | RNASELP2RY2ADORA1SMN1; SMN2DPP4 | |
| Adenosine SCHEMBL2248919 | 0.76 | ADORA3 (0.74) | RNASELP2RY2ADORA1SMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370451-A2 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | Chiralgen, Ltd. (JP) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010064146-A2 | METHOD FOR THE SYNTHESIS OF PHOSPHORUS ATOM MODIFIED NUCLEIC ACIDS | CHIRALGEN, LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |