Phosphoric Acid

Phosphoric Acid

SCHEMBL2470285

F.O.O=P(O)(O)O.[AlH3].[KH].[KH].[NaH]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36
SLC34A1 Q06495 1/20 0.33
KDM4E B2RXH2 1/20 0.31
MMP2 P08253 1/20 0.31
THRB P10828 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FDPS P14324 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28201995 0.91 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
Phosphoric Acid SCHEMBL2927237 0.91
Phosphoric Acid SCHEMBL28503265 0.91
Phosphoric Acid SCHEMBL28325358 0.91
Phosphoric Acid SCHEMBL4580760 0.91 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
Phosphoric Acid SCHEMBL28970696 0.91
Phosphoric Acid SCHEMBL28398462 0.91
Phosphoric Acid SCHEMBL28899247 0.91 CA2 (0.42) CA2SLC34A1KDM4EMMP2THRB
Phosphoric Acid SCHEMBL4050805 0.91
Phosphoric Acid SCHEMBL27738710 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113403619-A near-infrared/pH dual-response iodine-loaded titanium alloy implant and preparation method thereof 浙江大学 2021-09-17 CN claimed
EP-3586882-B1 ANTIBACTERIAL BIOLOGICAL IMPLANT PROSTEC CO LTD (JP) 2023-02-22 EP disclosed
EP-3981444-A1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS Biomet Manufacturing, LLC (US) 2022-04-13 EP disclosed
EP-3586883-B1 METHOD FOR PRODUCING ANTIBACTERIAL BIOLOGICAL IMPLANT PROSTEC CO LTD (JP) 2021-11-17 EP disclosed
US-20210186703-A1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS BIOMET MFG LLC (US) 2021-06-24 US disclosed
US-10980914-B2 Antibacterial biological implant PROSTEC CO., LTD. (JP) 2021-04-20 US disclosed
EP-3391915-B1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS BIOMET MFG LLC (US) 2021-04-14 EP disclosed
US-10940234-B2 Method for producing antibacterial biological implant PROSTEC CO., LTD. (JP) 2021-03-09 US disclosed
US-10893944-B2 Methods of modifying the porous surface of implants BIOMET MANUFACTURING, LLC (US) 2021-01-19 US disclosed
US-10668187-B2 Medical supplies and method of producing the same PROSTEC CO., LTD. (JP) 2020-06-02 US disclosed
EP-3391915-A2 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS Biomet Manufacturing, LLC (US) 2018-10-24 EP disclosed
US-20180280143-A1 METHODS OF MODIFYING THE POROUS SURFACE OF IMPLANTS BIOMET MANUFACTURING, LLC 2018-10-04 US disclosed
US-20180243483-A1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO LTD (JP) 2018-08-30 US disclosed
US-9889231-B2 Medical supplies and method of producing the same PROSTEC CO., LTD. (JP) 2018-02-13 US disclosed
CN-102281906-B Medical part and manufacturing method therefor PROSTEC CO LTD 2014-08-27 CN disclosed
US-20130240365-A1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO., LTD. (JP) 2013-09-19 US disclosed
EP-2371398-B1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO LTD (JP) 2013-05-15 EP disclosed
US-20110313539-A1 MEDICAL SUPPLIES AND METHOD OF PRODUCING THE SAME PROSTEC CO., LTD. (JP) 2011-12-22 US disclosed
CN-102281906-A Medical part and manufacturing method therefor 2011-12-14 CN disclosed
EP-2371398-A1 MEDICAL PART AND MANUFACTURING METHOD THEREFOR Prostec Co., Ltd. (JP) 2011-10-05 EP disclosed