SCHEMBL2470360

SCHEMBL2470360

Nc1[c]c(S(=O)(=O)O)cc2cc(S(=O)(=O)O)cc(O)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.61
CASP6 P55212 4/20 0.45
NSD2 O96028 3/20 0.45
DUSP3 P51452 2/20 0.45
PTPN5 P54829 2/20 0.45
PTPN11 Q06124 2/20 0.45
PTPN1 P18031 2/20 0.42
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 4/20 0.41
PRMT1 Q99873 2/20 0.41
APEX1 P27695 1/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2C9 P11712 3/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 1/20 0.40
ING2 Q9H160 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
MAPK1 P28482 1/20 0.35
DNASE1L3 Q13609 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11340204 0.84 NT5E (0.45) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL2213528 0.84 NT5E (0.56) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1413164 0.80 NT5E (0.39) NT5EALDH1A1HSD17B10
SCHEMBL8377402 0.78 NT5E (0.61) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL564558 0.77 NT5E (0.74) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL66310 0.77 NT5E (0.74) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL11502500 0.77 NT5E (0.74) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL29429654 0.77 NT5E (0.74) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL150291 0.76 NT5E (1.00) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL6840785 0.76 NT5E (1.00) NT5ECASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed
EP-2885357-B1 INKS FOR INK-JET PRINTING FUJIFILM IMAGING COLORANTS INC (US) 2018-06-13 EP disclosed
US-9540532-B2 Inks for ink-jet printing FUJIFILM IMAGING COLORANTS, INC. (US) 2017-01-10 US disclosed
US-20150184013-A1 Inks for Ink-Jet Printing FUJIFILM IMAGING COLORANTS, INC. 2015-07-02 US disclosed
EP-2885357-A1 INKS FOR INK-JET PRINTING Fujifilm Imaging Colorants, Inc. (US) 2015-06-24 EP disclosed
WO-2014027179-A1 INKS FOR INK-JET PRINTING FUJIFILM IMAGING COLORANTS, INC. (US) 2014-02-20 WO disclosed
EP-2539406-A1 INKS Fujifilm Imaging Colorants, Inc. (US) 2013-01-02 EP disclosed
US-20120306962-A1 INKS FUJIFILM IMAGING COLORANTS, INC. 2012-12-06 US disclosed
WO-2011104522-A1 INKS FUJIFILM IMAGING COLORANTS, INC. (US) 2011-09-01 WO disclosed
US-20050203286-A1 Environmental protection series of reactive dyestuffs and their use EVERLIGHT USA, INC. (US) 2005-09-15 US disclosed
US-6635747-B2 Soluble monoazo dyes which provide prints exhibiting high lightfastness and good waterfastness when incorporated into inks AVECIA LIMITED (GB) 2003-10-21 US disclosed
US-20030120047-A1 Dyes, inks and their use in ink-jet printing AVECIA INKJET LIMITED (GB) 2003-06-26 US disclosed
EP-1257601-A1 DYES, INKS AND THEIR USE IN INK-JET PRINTING Avecia Limited (GB) 2002-11-20 EP disclosed
EP-1248820-A2 DISAZO COMPOUNDS, THEIR PREPARATION AND THEIR USE AS DYESTUFFS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2002-10-16 EP disclosed
WO-2001059012-A1 DYES, INKS AND THEIR USE IN INK-JET PRINTING AVECIA LIMITED (GB) 2001-08-16 WO disclosed
WO-2001049791-A2 DISAZO COMPOUNDS, THEIR PREPARATION AND THEIR USE AS DYESTUFFS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-07-12 WO disclosed
US-6187912-B1 FIBER-REACTIVE, WATER-SOLUBLE DISAZO COMPOUNDS WHICH ARE CAPABLE OF DYEING FIBER MATERIAL IN HIGH INTENSITY AND WITH GOOD FASTNESS PROPERTIES DYSTAR TEXTIFARBEN GMBH & CO. (DE) 2001-02-13 US disclosed
US-6171349-B1 COLORFASTNESS TO LAUNDERING-OXIDATIVE BLEACH RESPONSE EVERLIGHT USA, INC. 2001-01-09 US disclosed
US-6126700-A COMPRISING A DISAZO BLACK REACTIVE DYE OF GIVEN FORMULA, A BLACK OR BLUE REACTIVE DYE WITH GOOD FASTNESS OF OXIDATIVE BLEACH AND WASHFASTNESS, AND A RED, ORANGE, YELLOW OR OTHER SHADE REACTIVE AZO DYE OF GIVEN FORMULA EVERLIGHT USA, INC. (US) 2000-10-03 US disclosed
US-5952476-A Red reactive dyestuffs EVERLIGHT USA, INC. (US) 1999-09-14 US disclosed